Month: May 2018

May 10, 2018
EAHAD defines principles of inhibitor management

Principles for the management of patients who develop inhibitors have been developed by a multidisciplinary group of health professionals and patients under the auspices of EAHAD and the European Haemophilia Consortium. The document, which emphasises the importance of a centralised, holistic approach, includes ten statements: 1. Awareness of the incidence of inhibitors and risk factors …

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Perioperative replacement therapy in haemophilia B

Targeting Factor IX levels in patients with. Haemophilia B who are undergoing surgery is ‘complex and suboptimal’ but the incidence of bleeding complications is low – so say specialists from the UK and the Netherlands (Haemophilia 2018;April 29. DOI: 10.1111/hae.13469). The study assessed outcomes in 255 minor and major surgical carried out between 2000 and …

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Cost of gene therapies might be millions per patient

The cost of gene therapy for patients with haemophilia could be as high as $2 million per person, according to US analysts. Early estimates of the cost of gene therapy for haemophilia put the figure at $350,000 – $500,000 per patient but investment bankers Leerink Partners are predicting far higher costs by using the price …

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Stem cell therapy for haemophilia B?

US researchers have shown that it is possible to engineer stem cells to correct the gene defect that causes haemophilia B and use them to restore normal clotting in an animal model. The Salk Institute (www.salk.edu) says its work demonstrates the principle that stem cell therapy could work in humans, potentially offering a less expensive …

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Stem cell therapy for haemophilia B?

US researchers have shown that it is possible to engineer stem cells to correct the gene defect that causes haemophilia B and use them to restore normal clotting in an animal model. The Salk Institute (www.salk.edu) says its work demonstrates the principle that stem cell therapy could work in humans, potentially offering a less expensive …

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