Is it time to move beyond the 1% target?

In haemophilia A, prophylaxis aims to increase trough levels of factor VIII above 1% through regular, long term intravenous administration of concentrates, with the ultimate aim of converting a severe bleeding phenotype to a moderate phenotype. In a Bayer-sponsored symposium on prophylaxis at the ISTH meeting in Amsterdam, Professor Cedric Hermans from Louvain, Belgium, noted …