May 10, 2019

Moderate haemophilia ‘neglected’

The available evidence shows that moderate haemophilia is a ‘neglected disease’, according to the eminent Swedish haemophilia specialist Eric Berntorp (Haemophilia 2019 Mar;25(2):187-188).

He was commenting on the THUNDER study (Haemophilia 2019;25:205-212). Using Haemtrack data, this suggested that people with moderate haemophilia in the UK are undertreated because their annual bleeding rate and joint status was similar to that of people with severe haemophilia. Berntorp suggests one explanation may be that factor prophylaxis may be delayed in people with moderate haemophilia until joint damage is clinically apparent, by which time the higher risk of bleeding has been established.